Here in the Uk Years ago We had a few vans fitted with these doors and Like yours they rattled & whistled

And what the owners did was to check the Door carrier bolts (top and bottom) were secure Meant standing on a step ladder with a torque bar and socket Also tighten all the bolts on the Runner bars Will be a bit hidden if there is a sliding runner with Bearing ...Do try to brusgh the muck out Bit dirty Sorry!Might hide a bolt? Can Move the weather seals if allowed to build up
Next the Dirty Job...Buy a Tub of LM grease from the Motor Parts store (cheap) It will last you years and is good for most general Jobs around the house Too
After Tightening,Smear this with your finger over the tracks and on the wheels on the door if they are in view? Put too much on. You'll have grease over the van seats and on your clothing

Open and close the doors and the action will be a Lot smoother as the grease spreads over the hidden parts
As regards the Weather seals not too much you can do,bar check they are inline and Not
perished Though you can get any cheap Liquid Dish cleaner and apply it neat to the rubber and it will put some flex back into a tired seal or to push in a seal easy

Ps Tire fitters use it to Fit New tires