I had found an article about the affect of the artificial sweetener on rats on Los Angeles Times.
Casting doubt on the benefit of low-calorie sweeteners, research released Sunday reported that rats on diets containing saccharin gained more weight than rats given sugary food.
The study in the journal Behavioral Neuroscience found that the calorie-free artificial sweetener appeared to break the physiological connection between sweet tastes and calories, driving the rats to overeat.
Lyn M. Steffen, an associate professor of epidemiology at the University of Minnesota, who was not involved in the latest report, said the study offered a possible explanation for the unexpected association between obesity and diet soda found in recent human studies.
Researchers have puzzled over whether diet soda is a marker for poor eating habits or diet soda ingredients cause people to put on pounds, she said. "This rat study suggests a component of the artificial sweetener may be responsible for the weight gain."