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Chromophobes are presumed to be "empty" cells, having already released their granules of hormone. These are cells that have minimal or no hormonal content. Many of the chromophobes may be acidophils or basophils that have degranulated and thereby are depleted of hormone. Some chromophobes may also represent stem cells that have not yet differentiated into hormone-producing cells. Basophilic staining cells produce the hormones that specifically act on other endocrine organs. Acidophils produce growth hormone and prolactin. More Hereand Here
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