Does anyone know if Chronic Venous Insufficiency, can eventually cause gangrene? If it can, are there any procedures that can be done before it get to this stage? Compression hose are already being worn.

gangrene means tissue death; there are many forms (some people only think of "gas gangrene" when they hear of it.) Yes, venous insufficiency can cause it, when it gets to the stage of chronic swelling, darkening of the skin, etc. When the circulation is thus affected, ulceration (open sores) of the skin, especially near the ankle can occur. This, by definition, is gangrene (death of an area of skin tissue); the bigger danger is getting spreading infection from the ulceration. The congested tissue doesn't fight infection very well. It's a difficult problem. Most causes of venous insufficiency aren't amenable to "cure." (Some surgeons have tried transferring veins with normal valves into the area: it's not widely done so far.) Usually it happens because the valves in the veins have been destroyed, and there is so far no way to replace or repair them. Compression hose is by far the most important measure; having well-fitted (almost never is it best to have them go above the knee) and properly firm, and worn virtually all the time you're not in bed. Professional fitting is usually best. Sometimes pneumatic pump devices are used, especially at night to reduce swelling to allow better fit of hose during the day. Surgery usually consists of stripping away the surface veins to direct more circulation to the deeper veins. A vascular surgeon would be a place to get an evaluation to see where you are in the spectrum of therapeutic options. Most reputable vascular surgeons consider surgery a last resort.

Thanks Sid, for your reply. I wish it could have been a different answer, but the truth will have to be faced, sooner or later.