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Diamond Enthusiast

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Posted
New Antibiotics Fight Resistant Staph

This news article provides a little light at the end of the tunnel.. or perhaps a bit of torch-light to luminate our path... check it out:

quote:
One of a new line of synthetic antibiotics is showing promise in defeating deadly "superbugs," highly drug-resistant staph bacteria that are an increasing source of hospital-based infections.

"We are the first to demonstrate this unique strategy, which could provide a new line of defense against the growing problem of antibiotic resistance," said study leader Shahriar Mobashery, a chemist at Notre Dame University. "As scientists, we're trying to stay one step ahead of the bacteria. The more strategies there are to fight resistance, the better."

In preliminary lab tests, the compounds were effective against vancomycin-resistant MRSA, a rare but extremely deadly staph strain for which treatment options are very limited.

The drugs are synthetic forms of cephalosporin, a broad-spectrum antibiotic closely related to penicillin, according to research being presented at the annual meeting of the American Chemical Society in Washington, D.C.

The new antibiotics appear to kill bacteria by acting as a "wolf in sheep's clothing," masquerading as components of the bacteria's cell wall in order to deactivate an enzyme that functions as a key bacterial defense mechanism.



It is amazing that we discovered, used and then over-used antibiotics within a span of less than 100 years. These medications on which we have become so dependent have actually existed (in a form deliberately created and used commercially) for less than a century.

Brief History of Antibiotics
 
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